Mouse Anti-Rat CD169

Mouse Anti-Rat CD169 (0.1 mg)

DS-MB-00408
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Antigen Information

Protein Name & Synonyms:
CD169
Target Species:
  • Rat

Antibody Specifications

Applications:
Immunohistology - Frozen, Flow Cytometry, Immunofluorescence, Immunoprecipitation
Concentration:
IgG concentration 0.5 mg/ml
Species Reactivity:
Rat

Specificity

This product recognizes the rat CD169 cell surface antigen, a 185kD molecule expressed by macrophages, predominately confined to lymphoid organs only. Monocytes and granulocytes are negative. No other cell types are positive. The most conspicious property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly. Furthermore, macrophages in (auto-immune) diseased tissues express the ED3 antigen. In healthy tissue no expression occurs. CD169 is a receptor for glycoconjugates containing sialic acid.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Rat Spleen cell homogenate
Preservative:
0.09%Sodium Azide
This product
Spleen cells from immunised BALB/c mice were fused with cells of the SP2/0-Ag 14 mouse myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.