Purified His-tagged RPS6KA3 protein(Fragment) was used to produced this monoclonal antibody.
Clonality
Monoclonal
Species
Human, Mouse
Introduction
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).
Specificity
Other Names
RPS6KA3; ISPK1; MAPKAPK1B; RSK2; Ribosomal protein S6 kinase alpha-3; 90 kDa ribosomal protein S6 kinase 3; Insulin-stimulated protein kinase 1; MAP kinase-activated protein kinase 1b; Ribosomal S6 kinase 2; pp90RSK2
NCBI Accession #
NP_004577.1
Other Accession #
P18654; NP_004577.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
83736
Recommended Dilutions
WB: 1:500-16000
RPS6KA3 Antibody (Cat# 102-10238) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RPS6KA3 antibody detected the RPS6KA3 protein (arrow).
RPS6KA3 Antibody (Cat# 102-10238) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the RPS6KA3 antibody detected the RPS6KA3 protein (arrow).
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
