This SERPINC1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from human SERPINC1.
Clonality
Monoclonal
Species
Human, Rat
Introduction
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Specificity
Other Names
SERPINC1; AT3; Antithrombin-III; Serpin C1
NCBI Accession #
NP_000479.1
Other Accession #
NP_000479.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
52602
Recommended Dilutions
WB: 1:100-1600
SERPINC1 Antibody (Cat# 102-10278) western blot analysis in rat liver tissue lysates (35ug/lane).This demonstrates the SERPINC1 antibody detected the SERPINC1 protein (arrow).
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
