Neuregulin-1, Heregulin-b1, NRG1-B1, NRG1 B1.

SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF TGDRCQNYVM ASFYKHLGIE FMEAE.

Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.

Sterile Filtered White lyophilized (freeze-dried) powder.

Lyophilized from a 0.2 um filtered solution in 1ÃÂPBS, pH 7.4 and 5% trehalose.

The ED50 was determined by the dose-dependent stimulation of the proliferation of human MCF-7 cells is less than 0.5ng/ml, corresponding to a specific activity of >,2.0Ã—106 units/mg.

Description

Recombinant Human Neuregulin-1/Heregulin-b1 produced in E.Coli is a single, non-glycosylated, polypeptide chain (a.a 177-241) containing 65 amino acids and having a total molecular mass of 7.5kDa. NRG1-B1 is purified by proprietary chromatographic techniques.

Stability & Storage

Storage/Stability

Lyophilized NRG1-B1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution NRG1-B1 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

Neuregulin-1, Heregulin-b1, NRG1-B1, NRG1 B1.

SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF TGDRCQNYVM ASFYKHLGIE FMEAE.

Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.

Sterile Filtered White lyophilized (freeze-dried) powder.

Lyophilized from a 0.2 um filtered solution in 1ÃÂPBS, pH 7.4 and 5% trehalose.

The ED50 was determined by the dose-dependent stimulation of the proliferation of human MCF-7 cells is less than 0.5ng/ml, corresponding to a specific activity of >,2.0Ã—106 units/mg.

Description

Stability & Storage

Storage/Stability

Size	50 µg, 1000 µg
Estimated Lead Time	2-3 weeks
Species	Human
Protein Name / Synonyms	Neuregulin-1, Heregulin-b1, NRG1-B1, NRG1 B1.
Expressed Region	SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF TGDRCQNYVM ASFYKHLGIE FMEAE.
Expression System	E. coli
Purity	Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Format	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	Lyophilized from a 0.2 um filtered solution in 1ÃÂPBS, pH 7.4 and 5% trehalose.
Activity	The ED50 was determined by the dose-dependent stimulation of the proliferation of human MCF-7 cells is less than 0.5ng/ml, corresponding to a specific activity of >,2.0Ã—106 units/mg.
Shipping Type	Ambient temperature
Storage	-20°C

Size	50 µg, 1000 µg
Estimated Lead Time	2-3 weeks
Species	Human
Protein Name / Synonyms	Neuregulin-1, Heregulin-b1, NRG1-B1, NRG1 B1.
Expressed Region	SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF TGDRCQNYVM ASFYKHLGIE FMEAE.
Expression System	E. coli
Purity	Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Format	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	Lyophilized from a 0.2 um filtered solution in 1ÃÂPBS, pH 7.4 and 5% trehalose.
Activity	The ED50 was determined by the dose-dependent stimulation of the proliferation of human MCF-7 cells is less than 0.5ng/ml, corresponding to a specific activity of >,2.0Ã—106 units/mg.
Shipping Type	Ambient temperature
Storage	-20°C

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