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ISO 13485:2016 cGMP

Noggin, Mouse Recombinant

Catalog #: 228-11161

Product Description

Specifications

Size20 µg, 1000 µg
Estimated Lead Time2-3 weeks
SpeciesMouse
Accession Number
P97466
Gene Id
18121
Protein Name / Synonyms
Noggin, SYM1, SYNS1, NOG.
Expressed Region
MQHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLLGGHYDPGFMATSPPEDRPGGGGGPAGGAEDLAELDQLLRQRPSGAMPSEIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYAWNDLGSRFWPRYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQRRGQRCGWIPIQYPIISECKCSC.
Expression SystemE. coli
Purity
Greater than 95.0% as determined by SDS-PAGE.
Format
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2 umfiltered solution in 30% CH3CN, 0.1% TFA.
Activity
The ED50 was determined by its ability to inhibit 5.0 ng/ml of BMP-4 induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 1-2ng/ml of NOGGIN, corresponding to a specific activity of 500,000-1,000,000 u
Research AreaCardiovascular Disease
Shipping TypeAmbient temperature
Storage-20°C

Description

Description

Noggin Mouse Recombinant produced in E.Coli is a non-glycosylated, non-disulfide-linked homodimer consisting of two 206 amino acid polypeptide chains, having a total molecular mass of approximately 46.2 kDa (each chain 23.1 kDa).Noggin Mouse is purified by proprietary chromatographic techniques.

Stability & Storage

Storage/Stability
Lyophilized Mouse Noggin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Mouse Noggin should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.