The human androgen receptor protein belongs to the class of nuclear receptors called activated class I steroid receptors, which also includes glucocorticoid receptor, progesterone receptor, and mineralocorticoid receptor. These receptors recognize canonical androgen response elements (AREs), which are inverted repeats of 5-prime-TGTTCT-3-prime. The major domains of AR include N- and Cterminal activation domains, which are designated activation function-1 (AF-1) and AF-2, a ligandbinding domain, and a polyglutamine tract. Human androgen receptor contain 920 amino acids and having a molecular mass of 110 kDa.

The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.

The rabbit anti-human AR antibody detects specifically target derived from human recombinant protein as well as MCF7 cell lysate at various concentrations. Cross reactivity with mouse and rat are expected from sequence similarity.

Goat Anti-Androgen Receptor, with HRP-conjugated secondary antibody (cat# ER-04-0011) Recombinant Human Androgen Receptor?Cat# RB-14-0003P