Rabbit Anti-BRD4 (C-term) Antibody, 400 µl
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O60885|Q9ESU6 |
| Gene Id | 23476 |
| Gene Symbols | BRD4 |
| Protein Name / Synonyms | Bromodomain-containing protein 4, Protein HUNK1, BRD4, HUNK1 |
| Clonality | Polyclonal |
| Clone | RB3422 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people.
Other Information
NCBI Accession #
NP_055114.1;NP_490597.1
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Calculated Molecular Weight (Da)
152219
Antigen Source
Human
Images
IHC-P (1:50~100)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.