Rabbit Anti-CASP6 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P55212 |
| Gene Id | 839 |
| Gene Symbols | CASP6 |
| Protein Name / Synonyms | CASP6 (C-term) |
| Clonality | Polyclonal |
| Preparation | This CASP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the C-terminal region of human CASP6. |
| Concentration (lot specific) | 0.370 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Apoptosis, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
CASP6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.
Specificity
Predicted Reactivity
Rat, Bovine
Other Names
CASP6; MCH2; Caspase-6; Apoptotic protease Mch-2; Caspase-6 subunit p18; Caspase-6 subunit p11
NCBI Accession #
NP_001217.2;NP_116787.1
Other Accession #
O35397; O08738; Q3T0P5
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
33310
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of anti-CASP6 Antibody (C-term) (Cat# 102-11883) in mouse liver tissue lysates (35ug/lane). CASP6 (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CASP6 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.