Rabbit Anti-Cdc25A (S78) Antibody, 400 µl
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P30304|P48965|P48964|A7MBD1 |
| Gene Id | 993 |
| Gene Symbols | CDC25A |
| Protein Name / Synonyms | M-phase inducer phosphatase 1, Dual specificity phosphatase Cdc25A, CDC25A |
| Clonality | Polyclonal |
| Clone | RB08125 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.
Other Information
NCBI Accession #
NP_001780.2;NP_963861.1
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
59087
Antigen Source
Human
Images
WB (1:1000)
Cdc25A Antibody (S78) (Cat.#102-26993) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the Cdc25A antibody detected the Cdc25A protein (arrow).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.