Rabbit Anti-CREBL1 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Hamster |
| Host Species | Rabbit |
| Accession Number | Q99941 |
| Gene Id | 1388 |
| Gene Symbols | ATF6B |
| Protein Name / Synonyms | CREBL1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This CREBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-589 amino acids from the C-terminal region of human CREBL1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
CREBL1 is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.
Specificity
Other Names
ATF6B; CREBL1; G13; Cyclic AMP-dependent transcription factor ATF-6 beta; Activating transcription factor 6 beta; Protein G13; cAMP response element-binding protein-related protein; cAMP-responsive element-binding protein-like 1; Processed cyclic AMP-dependent transcription factor ATF-6 beta
NCBI Accession #
NP_001129625.1;NP_004372.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
76709
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of lysates from Hela, HepG2 cell line and human placenta tissue lysate (from left to right), using CREBL1Antibody (C-term) (Cat# 102-16410). 102-16410 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane. |
 | CREBL1 Antibody (C-term) (Cat# 102-16410) western blot analysis in mouse NIH-3T3,CHO cell line and mouse cerebellum tissue lysates (35ug/lane).This demonstrates the CREBL1 antibody detected the CREBL1 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.