This antibody was produced from antiserum of rabbits immunized with a synthetic immunogen PDCD1:LQGAQPPSPEDGPGLWPPC).This antibody was produced from a rabbit immunized with this peptide conjugated with KLH.The IgG fraction was purified by Protein A affinity chromatography.
Immunogen Sequence
271-LQGAQPPSPEDGPGLWPPC-288
Protein Name / Synonyms
PDCD1
Accession Number
A0A090BAM7
Recommended Applications
ELISA (recommended work dilution= 1:32,000)
Reconstitution
Product is supplied as a powder obtained from lyophilization of purified antibody in 1X PBS, aliquot using ddH2O. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml.
Description
PDCD1 encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Storage
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Expiration:
12 months from the date of shipment when stored properly.
