This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.

WB 1:500 - 1:1000

Recombinant fusion protein containing a sequence corresponding to amino acids 214-373 of human DRD2 (NP_000786.1).

Unmodified

Store at -20°. Avoid freeze / thaw cycles.