This gene encodes an EF-hand-containing calcium binding protein. The encoded protein likely plays a role in calcium homeostasis. Mutations in this gene have been associated with susceptibility to juvenile myoclonic epilepsy and juvenile absence epilepsy. Alternatively spliced transcript variants have been described.
Dilutions
WB 1:500 - 1:2000 IHC 1:50 - 1:200
Format
Calculated MW
31kDa/72kDa/73kDa
Observed MW
74kDa
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 391-640 of human EFHC1 (NP_060570.2).
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of various cell lines, using EFHC1 antibody (144-08002) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human stomach using EFHC1 antibody (144-08002) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using EFHC1 antibody (144-08002) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse stomach using EFHC1 antibody (144-08002) at dilution of 1:100 (40x lens).
Expiration:
12 months from the date of shipment when stored properly.
