Rabbit Anti-FIBB (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P02675 |
| Gene Id | 2244 |
| Gene Symbols | FGB |
| Protein Name / Synonyms | FIBB (C-term) |
| Clonality | Polyclonal |
| Preparation | This FIBB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-357 amino acids from the C-terminal region of human FIBB. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Specificity
Predicted Reactivity
Rat
Other Names
FGB; Fibrinogen beta chain; Fibrinopeptide B
NCBI Accession #
NP_001171670.1;NP_005132.2
Other Accession #
P14480; Q8K0E8
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
55928
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of FIBB antibody (C-term) (Cat# 102-16797) in mouse liver tissue lysates (35ug/lane). FIBB (arrow) was detected using the purified Pab. |
 | FIBB Antibody (C-term) (Cat# 102-16797) IHC analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FIBB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.