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770-729-2992
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Product Specifications
Size:
0.1 ml
Protein Information
Protein Name & Synonyms:
GAP43
Target Species:
- Feline (cat)
Antibody Specifications
Applications:
Immunohistology - Frozen, Immunofluorescence, Immunoprecipitation, Western Blotting
Preparation:
Antisera to GAP43 were raised by repeated immunisations of rabbits with highly purified antigen.
Species Reactivity:
Cat, Human, monkey, mouse, rat, feline
Specificity
This product recognizes the protein designated GAP43, a neuronal protein that is expressed at elevated levels during development and also during regenerative axon growth.
GAP43 (also known as neuromodulin, pp46, B-50, Protein F1 and calmodulin-binding protein P-57) is a protein of approximately 25kD that migrates on SDS-PAGE gels with an apparent size of 40-50kD. The aberrant migration is due to the unusually low abundance of hydrophobic amino acid residues. GAP43 is found tightly associated with neuronal membranes due to palmitoylation. The solubilised protein binds calmodulin, although this is reduced following protein kinase C phosphorylation of GAP43.
GAP43 (also known as neuromodulin, pp46, B-50, Protein F1 and calmodulin-binding protein P-57) is a protein of approximately 25kD that migrates on SDS-PAGE gels with an apparent size of 40-50kD. The aberrant migration is due to the unusually low abundance of hydrophobic amino acid residues. GAP43 is found tightly associated with neuronal membranes due to palmitoylation. The solubilised protein binds calmodulin, although this is reduced following protein kinase C phosphorylation of GAP43.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Serum - liquid
Format Type:
Serum
Preparation
Antisera to GAP43 were raised by repeated immunisations of rabbits with highly purified antigen.
Immunogen:
Purified GAP43 from cat brain.
Preservative:
0.02% Sodium Azide (NaN3)
Expiration:
12 months from the date of shipment when stored properly.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
