Rabbit Anti-GAP43

Rabbit Anti-GAP43

DS-PB-00842
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Antigen Information

Protein Name & Synonyms:
GAP43
Target Species:
  • Feline (cat)

Antibody Specifications

Applications:
Immunohistology - Frozen, Immunofluorescence, Immunoprecipitation, Western Blotting
Preparation:
Antisera to GAP43 were raised by repeated immunisations of rabbits with highly purified antigen.
Species Reactivity:
Cat, Human, monkey, mouse, rat, feline

Specificity

This product recognizes the protein designated GAP43, a neuronal protein that is expressed at elevated levels during development and also during regenerative axon growth.

GAP43 (also known as neuromodulin, pp46, B-50, Protein F1 and calmodulin-binding protein P-57) is a protein of approximately 25kD that migrates on SDS-PAGE gels with an apparent size of 40-50kD. The aberrant migration is due to the unusually low abundance of hydrophobic amino acid residues. GAP43 is found tightly associated with neuronal membranes due to palmitoylation. The solubilised protein binds calmodulin, although this is reduced following protein kinase C phosphorylation of GAP43.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Serum - liquid
Format Type:
Serum

Preparation

Antisera to GAP43 were raised by repeated immunisations of rabbits with highly purified antigen.

Immunogen:
Purified GAP43 from cat brain.
Preservative:
0.02% Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.