Rabbit Anti-GLDC (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P23378 |
| Gene Id | 2731 |
| Gene Symbols | GLDC |
| Protein Name / Synonyms | GLDC (N-term) |
| Clonality | Polyclonal |
| Preparation | This GLDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human GLDC. |
| Concentration (lot specific) | 0.280 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
Specificity
Other Names
GLDC; GCSP; Glycine dehydrogenase [decarboxylating], mitochondrial; Glycine cleavage system P protein; Glycine decarboxylase
NCBI Accession #
NP_000161.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
112730
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of GLDC Antibody (N-term) (Cat# 102-18291) in mouse liver tissue lysates (35ug/lane). GLDC (arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.