Rabbit Anti-HDAC1 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | Q13547 |
| Gene Id | 3065 |
| Gene Symbols | HDAC1 |
| Protein Name / Synonyms | HDAC1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This HDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HDAC1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IF |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Specificity
Other Names
HDAC1; RPD3L1; Histone deacetylase 1
NCBI Accession #
NP_004955.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
55103
Recommended Dilutions
WB: 1:1000; IF: 1:10-50
 | HDAC1 Antibody (M1) (Cat# 102-10903) western blot analysis in Hela,K562,mouse NIH/3T3 cell line and mouse testis,rat testis and spleen tissue lysates (35ug/lane).This demonstrates the HDAC1 antibody detected the HDAC1 protein (arrow). |
 | Confocal immunofluorescent analysis of HDAC1 Antibody (N-term)(Cat# 102-10903) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.