Rabbit Anti-Human AGR2 (Center) Antibody, 400 ul
Loading...
Loading...
Loading...
Loading...
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O95994 |
| Gene Id | 10551 |
| Gene Symbols | AGR2 |
| Protein Name / Synonyms | AGR2 (Center) |
| Clonality | Polyclonal |
| Preparation | This AGR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-124 amino acids from the Central region of human AGR2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Anterior gradient 2 (AGR2) is known as a cancer cell marker specifically up-regulated in response to depletion of serum and oxygen. AGR2 has been identified as a tumor marker in primary and secondary cancer lesions, and as a marker for detection of circulating tumor cells (CTCs). Elevated levels of AGR2 are known to increase the metastatic potential of cancer cells, but conditions leading to increased expression of AGR2 are not well understood.
Specificity
Predicted Reactivity
Mouse, Zebrafish
Other Names
AGR2; AG2; Anterior gradient protein 2 homolog; HPC8; Secreted cement gland protein XAG-2 homolog
NCBI Accession #
NP_006399.1
Other Accession #
O88312; Q5RZ65
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
19979
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of lysates from ZR-75-1, HT29 cell line (from left to right), using AGR2 Antibody (Center)(Cat# 102-16720). 102-16720 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane. |
 | AGR2 Antibody (Center) (Cat# 102-16720) western blot analysis in HT29,MCF-7,ZR-75-1 cell line lysates (35ug/lane).This demonstrates the AGR2 antibody detected the AGR2 protein (arrow). |
 | AGR2 Antibody (Center) (Cat# 102-16720) western blot analysis in HT29,MCF-7,ZR-75-1 cell line lysates (35ug/lane).This demonstrates the AGR2 antibody detected the AGR2 protein (arrow). |
 | Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with AGR2 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.