Rabbit Anti-Human AKR1B1 (Center) Antibody, 400 ul
Loading...
Loading...
Loading...
Loading...
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P15121 |
| Gene Id | 231 |
| Gene Symbols | AKR1B1 |
| Protein Name / Synonyms | AKR1B1 (Center) |
| Clonality | Polyclonal |
| Preparation | This AKR1B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-135 amino acids from the Central region of human AKR1B1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IF, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.
Specificity
Other Names
AKR1B1; ALDR1; Aldose reductase; Aldehyde reductase; Aldo-keto reductase family 1 member B1
NCBI Accession #
NP_001619.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
35853
Recommended Dilutions
WB: 1:1000; IF: 1:10-50; IHC: 1:10-50
 | Western blot analysis of anti-AKR1B1 Pab (Cat# 102-15107) in Jurkat cell line lysates (35ug/lane).AKR1B1 (arrow) was detected using the purified Pab. |
 | Western blot analysis of AKR1B1 (arrow) using rabbit polyclonal AKR1B1 Antibody (Center) (Cat# 102-15107). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the AKR1B1 gene. |
 | Confocal immunofluorescent analysis of AKR1B1 Antibody (Center)(Cat# 102-15107) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
 | Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with AKR1B1 antibody (Center) (Cat# 102-15107), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.