Rabbit Anti-Human BAG2 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O95816 |
| Gene Id | 9532 |
| Gene Symbols | BAG2 |
| Protein Name / Synonyms | BAG2 (C-term) |
| Clonality | Polyclonal |
| Preparation | This BAG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the C-terminal region of human BAG2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq].
Specificity
Predicted Reactivity
Mouse, Bovine
Other Names
BAG2; BAG family molecular chaperone regulator 2; Bcl-2-associated athanogene 2
NCBI Accession #
NP_004273.1
Other Accession #
Q91YN9; Q3ZBG5; NP_004273.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
23772
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | BAG2 Antibody (C-term) (Cat# 102-12282) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the BAG2 antibody detected the BAG2 protein (arrow). |
 | BAG2 Antibody (C-term) (102-12282)immunohistochemistry analysis in formalin fixed and paraffin embedded human ovarian carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BAG2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.