Bcl-w,which is a member of the BCL-2 protein family, form hetero- or homodimers and act as anti- and pro-apoptotic regulators. This protein has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons.Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.

The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.

The antibody can specifically bind to its immunogen, and did not show any cross reactivity with unrelated antigens in ELISA. The specificity for binding to recombinant protein, cellular protein and native antigen is not defined. Cross reactivity with mouse and rat Bcl-w has not yet been tested.

Rabbit Anti-bcl-2 Antibody(Cat#RB-02-0024) Goat Anti-Human BCL-2 Binding Component 3 Antibody(Cat#DS-PB-00241) RayBio^® Human Apoptosis Array 1 (2) (Cat# AAH-APO-1-2) Bcl-2 ELISA Kit(Cat#ELH-Bcl2-001)