Rabbit Anti-Human Bmf BH3 Domain Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q96LC9 |
| Gene Id | 90427 |
| Gene Symbols | BMF |
| Protein Name / Synonyms | Bmf BH3 Domain |
| Clonality | Polyclonal |
| Preparation | This Bmf BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-150 amino acids from human Bmf BH3 Domain. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Bmf belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis.
Specificity
Predicted Reactivity
Mouse
Other Names
BMF; Bcl-2-modifying factor
NCBI Accession #
NP_001003940.1;NP_001003942.1;NP_001003943.1;NP_277038.1
Other Accession #
Q91ZE9
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
20508
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of anti-Bmf BH3 Domain Antibody (Cat# 102-11873) in A2058 cell line lysates (35ug/lane). Bmf(arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.