Rabbit Anti-Human CAD (Center)

Rabbit Anti-Human CAD (Center) Antibody, 400 ul
In stock

Product Description


Size 400 µl
Protein Name / Synonyms CAD (Center)
Accession Number P27708
Gene Symbols CAD
Gene Id 790
Concentration (lot specific) 0.290 mg/ml
Preparation This CAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-809 amino acids from the Central region of human CAD.
Host Species Rabbit
Clonality Polyclonal
Species Human


The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.


Predicted Reactivity
Other Names
CAD; CAD protein; Glutamine-dependent carbamoyl-phosphate synthase; Aspartate carbamoyltransferase; Dihydroorotase
NCBI Accession #
Other Accession #
B2RQC6; NP_004332.2


Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
CAD Antibody (Center) (Cat# 102-10942) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CAD antibody detected the CAD protein (arrow).
CAD Antibody (Center) (Cat# 102-10942)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CAD Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
CAD Antibody (Center) (Cat# 102-10942) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source



2-8°C (short-term); -20°C (long-term)
12 months from the date of shipment when stored properly.
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