Rabbit Anti-Human CAMK2A (CAMK2 alpha) (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9UQM7 |
| Gene Id | 815 |
| Gene Symbols | CAMK2A |
| Protein Name / Synonyms | CAMK2A (CAMK2 alpha) (C-term) |
| Clonality | Polyclonal |
| Preparation | This CAMK2A (CAMK2 alpha) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-478 amino acids from the C-terminal region of human CAMK2A (CAMK2 alpha). |
| Concentration (lot specific) | 1.640 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
CAMK2A; CAMKA; KIAA0968; Calcium/calmodulin-dependent protein kinase type II subunit alpha
NCBI Accession #
NP_741960.1
Other Accession #
P11275; P11798
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
54088
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of anti-CAMK2 alpha C-term Pab (Cat# 102-17182) in 293 cell lysate. CAMK2 alpha (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
 | Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMK2 alpha Antibody (C-term) (Cat# 102-17182), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.