Rabbit Anti-Human CD2BP2 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O95400 |
| Gene Id | 10421 |
| Gene Symbols | CD2BP2 |
| Protein Name / Synonyms | CD2BP2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This CD2BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human CD2BP2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Research Area | Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
Specificity
Predicted Reactivity
Mouse
Other Names
CD2BP2; KIAA1178; CD2 antigen cytoplasmic tail-binding protein 2
NCBI Accession #
NP_001230575.1;NP_006101.1
Other Accession #
Q9CWK3; NP_006101.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
37646
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | CD2BP2 Antibody (N-term) (Cat# 102-10871) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD2BP2 antibody detected the CD2BP2 protein (arrow). |
 | CD2BP2 antibody(N-term) (Cat# 102-10871) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CD2BP2 antibody(N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | CD2BP2 Antibody (N-term) (Cat# 102-10871) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.