Rabbit Anti-Human CD320 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9NPF0 |
| Gene Id | 51293 |
| Gene Symbols | CD320 |
| Protein Name / Synonyms | CD320 (C-term) |
| Clonality | Polyclonal |
| Preparation | This CD320 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the C-terminal region of human CD320. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The CD320 antigen gene encodes the transcobalamin receptor (TCBLR). Cellular uptake of cobalamin (vitamin B12) is mediated by receptors expressed on the cell surface. Transcobalamin II (TCN2; MIM 613441), a plasma protein secreted by endothelial cells, binds the cobalamin absorbed in the distal ileum and carries 10 to 30% of total circulating cobalamin. CD320 encodes a transcobalamin receptor that binds TCN2-cobalamin at the plasma membrane and internalizes the complex by endocytosis (Quadros et al., 2009 [PubMed 18779389]).
Specificity
Other Names
CD320; 8D6A; CD320 antigen; 8D6 antigen; FDC-signaling molecule 8D6; Transcobalamin receptor; CD_antigen=CD320; Flags: Precursor
NCBI Accession #
NP_001159367.1;NP_057663.1
Other Accession #
NP_001159367.1; NP_057663.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
28991
Recommended Dilutions
WB: 1:1000
 | CD320 Antibody (C-term) (Cat# 102-11882) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the CD320 antibody detected the CD320 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.