Rabbit Anti-Human Cdc6 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q99741 |
| Gene Id | 990 |
| Gene Symbols | CDC6 |
| Protein Name / Synonyms | Cdc6 (N-term) |
| Clonality | Polyclonal |
| Preparation | This Cdc6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human Cdc6. |
| Concentration (lot specific) | 0.430 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Human Cdc6 is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
Specificity
Other Names
CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; p62(cdc6)
NCBI Accession #
NP_001245.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
62720
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of Cdc6 Antibody (N-term)(Cat# 102-16713) in Romas cell line lysates (35ug/lane). Cdc6 (arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.