Rabbit Anti-Human CDKN1B (C-term) Antibody, 400 ul
Loading...
Loading...
Loading...
Loading...
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P46527 |
| Gene Id | 1027 |
| Gene Symbols | CDKN1B |
| Protein Name / Synonyms | CDKN1B (C-term) |
| Clonality | Polyclonal |
| Preparation | This CDKN1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the C-terminal region of human CDKN1B. |
| Concentration (lot specific) | 0.450 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cardiovascular Disease, Cancer, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq].
Specificity
Other Names
CDKN1B; KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1
NCBI Accession #
NP_004055.1
Other Accession #
NP_004055.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
22073
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | CDKN1B Antibody (C-term) (Cat# 102-11951) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the CDKN1B antibody detected the CDKN1B protein (arrow). |
 | CDKN1B Antibody (C-term) (Cat# 102-11951)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CDKN1B Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.