Rabbit Anti-Human CFH (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P08603 |
| Gene Id | 3075 |
| Gene Symbols | CFH |
| Protein Name / Synonyms | CFH (Center) |
| Clonality | Polyclonal |
| Preparation | This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human CFH. |
| Concentration (lot specific) | 0.287 mg/ml |
| Recommended Applications | IF, Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Specificity
Other Names
CFH; HF; HF1; HF2; Complement factor H; H factor 1
NCBI Accession #
NP_000177.2
Other Accession #
NP_000177.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
139096
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; IF: 1:10-50
 | CFH Antibody (Center) (Cat# 102-10865) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CFH antibody detected the CFH protein (arrow). |
 | CFH antibody (Center) (Cat# 102-10865) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CFH antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of CFH Antibody (Center) (Cat# 102-10865) with A549 cell followed by Alexa Fluor® 489-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.