Rabbit Anti-Human CFL2 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9Y281 |
| Gene Id | 1073 |
| Gene Symbols | CFL2 |
| Protein Name / Synonyms | CFL2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This CFL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human CFL2. |
| Concentration (lot specific) | 0.480 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Specificity
Predicted Reactivity
Mouse, Bovine, Pig
Other Names
CFL2; Cofilin-2; Cofilin, muscle isoform
NCBI Accession #
NP_001230574.1;NP_068733.1;NP_619579.1
Other Accession #
Q5G6V9; P45591; Q148F1; NP_619579.1; NP_068733.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
18737
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of lysate from NCI-H1299 cell line, using CFL2 Antibody (N-term)(Cat# 102-12319). 102-12319 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane. |
 | CFL2 Antibody (N-term) (102-12319)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CFL2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.