Rabbit Anti-Human cIAP2 (BIRC3) (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q13489 |
| Gene Id | 330 |
| Gene Symbols | BIRC3 |
| Protein Name / Synonyms | cIAP2 (BIRC3) (N-term) |
| Clonality | Polyclonal |
| Preparation | This cIAP2 (BIRC3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-131 amino acids from the N-terminal region of human cIAP2 (BIRC3). |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cancer, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
BIRC3 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain.
Specificity
Other Names
BIRC3; API2; IAP1; MIHC; RNF49; Baculoviral IAP repeat-containing protein 3; Apoptosis inhibitor 2; C-IAP2; IAP homolog C; Inhibitor of apoptosis protein 1; RING finger protein 49; TNFR2-TRAF-signaling complex protein 1
NCBI Accession #
NP_001156.1;NP_892007.1
Other Accession #
NP_892007
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
68372
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | BIRC3 Antibody (S116) (Cat# 102-16648) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the BIRC3 antibody detected the BIRC3 protein (arrow). |
 | cIAP2 (BIRC3) antibody (N-term) (Cat# 102-16648)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of cIAP2 (BIRC3) antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.