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Antigen Information
Accession Number:
- NP_077720
Target Species:
- Human
Antibody Specifications
Applications:
ELISA (recommended work dilution= 1: 40,000(at least detecting 25ng/ml))
Immunogen Sequence:
GLSKGCFGLKLDRIGSMSGLGK
Preparation:
Immunogen was synthetic protein derived from Human CNP. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum followed by Protein A/G affinity chromatography.
Reconstitution:
Supplied as lyophilized and purified antibody originally containing PBS, without Preservative Stabilizers, such as Sodium Azide. Please avoid freeze-thaw cycles. The antibody is stable for at least years from the data of receipt when stored at -20°C to -70°C. Reconstituted antibody (recommended with H20 1 mg/ml) can also be aliquoted and stored frozen at -20°C to -70°C in a manual defrost freezer for months without detectable loss activity. Upon reconstitution, the antibody can be stored at 4°C for 1 month.
Species Reactivity:
Rabbit anti-Human Natriuretic Peptide Precursor C antibody detected specifically the target contained in tested samples (Serum and tissue). Cross reactivity with mouse and rat CNP has not yet been tested.
Description
Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide (CNP), encoded by a gene symbolized NPPC. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control. Natriuretic peptide precursor C homolog of mouse C type (CNP), most strongly expressed in the brain, also expressed in vascular endothelial cells and other tissues, present at extremely low level in circulation, potentially playing a paracrine/autocrine role.
Specificity
Rabbit anti-Human Natriuretic Peptide Precursor C antibody detected specifically the target contained in tested samples (Serum and tissue). Cross reactivity with mouse and rat CNP has not yet been tested.
Storage
Store at -20°C, if not intended for use within a month, keep it at 4°C and minimize freezing and thawing when use.
Related Products
RayBio® CNP EIA Kit for Serum, Plasma, Culture Supernantant and Cell Lysates (Cat# EIA-CNP-1 )
References
- Robert A Rose and Wayne R Giles, (2008) Natriuretic peptide C receptor signaling in the heart and vasculature. J Physiol.15;586 (Pt 2): 353366
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
