Rabbit Anti-Human CRFR2 (D35) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q13324 |
| Gene Id | 1395 |
| Gene Symbols | CRHR2 |
| Protein Name / Synonyms | CRFR2 (D35) |
| Clonality | Polyclonal |
| Preparation | This CRFR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from human CRFR2. |
| Concentration (lot specific) | 0.260 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Liaw et al. (1996) [PubMed 8536644] stated that there are 2 G protein-coupled corticotropin-releasing hormone (CRH; MIM 122560) receptors, CRHR1 (MIM 122561) and CRHR2, which they termed the CRF2 receptor. CRH is a 41-amino acid peptide synthesized in the hypothalamus that is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge.
Specificity
Other Names
CRHR2; CRF2R; CRH2R; Corticotropin-releasing factor receptor 2; Corticotropin-releasing hormone receptor 2
NCBI Accession #
NP_001189404.1;NP_001189410.1;NP_001189411.1;NP_001189412.1;NP_001874.2
Other Accession #
NP_001874.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
47688
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | CRFR2 Antibody (D35) (Cat# 102-11094) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CRFR2 antibody detected the CRFR2 protein (arrow). |
 | CRFR2 Antibody (D35)(Cat# 102-11094)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CRFR2 Antibody (D35) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | CRFR2 Antibody (D35) (Cat# 102-11094) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.