Rabbit Anti-Human DIO2 (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q92813 |
| Gene Id | 1734 |
| Gene Symbols | DIO2 |
| Protein Name / Synonyms | DIO2 (Center) |
| Clonality | Polyclonal |
| Preparation | This DIO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-191 amino acids from the Central region of human DIO2. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
DIO2 belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3).
Specificity
Predicted Reactivity
Pig
Other Names
DIO2; ITDI2; TXDI2; Type II iodothyronine deiodinase; 5DII; DIOII; Type 2 DI; Type-II 5'-deiodinase
NCBI Accession #
NP_000784.2;NP_001007024.1;NP_001229431.1;NP_001229432.1;NP_054644.1
Other Accession #
Q6QN12
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
30552
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | Western blot analysis of DIO2 Antibody (Center) (Cat# 102-18000) in MCF-7 cell line lysates (35ug/lane). DIO2 (arrow) was detected using the purified Pab. |
 | DIO2 Antibody (Center) (Cat# 102-18000) IHC analysis in formalin fixed and paraffin embedded mouse brain followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the mouse DIO2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | DIO2 Antibody (Center) (Cat# 102-18000) flow cytometric analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.