Rabbit Anti-Human EHMT1 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9H9B1 |
| Gene Id | 79813 |
| Gene Symbols | EHMT1 |
| Protein Name / Synonyms | EHMT1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This EHMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-233 amino acids from the N-terminal region of human EHMT1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
Specificity
Other Names
EHMT1; EUHMTASE1; GLP; KIAA1876; KMT1D; Histone-lysine N-methyltransferase EHMT1; Euchromatic histone-lysine N-methyltransferase 1; G9a-like protein 1; Histone H3-K9 methyltransferase 5; Lysine N-methyltransferase 1D
NCBI Accession #
NP_001138999.1;NP_079033.4
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
141466
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of EHMT1 (arrow) using rabbit polyclonal EHMT1 Antibody (N-term) (Cat# 102-10586). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the EHMT1 gene (Lane 2) (Origene Technologies). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.