Rabbit Anti-Human ENG (Center)

Rabbit Anti-Human ENG (Center) Antibody, 400 ul
$334.00
In stock
Code:
102-11006
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+

Product Description

Specifications

Size 400 µl
Protein Name / Synonyms ENG (Center)
Accession Number P17813
Gene Symbols ENG
Gene Id 2022
Concentration (lot specific) 0.300 mg/ml
Preparation This ENG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the Central region of human ENG.
Host Species Rabbit
Clonality Polyclonal
Species Human

Introduction

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specificity

Other Names
ENG; END; Endoglin; CD_antigen=CD105; Flags: Precursor
NCBI Accession #
NP_000109.1;NP_001108225.1;NP_001265067.1
Other Accession #
NP_001108225.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
70578
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
Western blot analysis of ENG (arrow) using rabbit polyclonal ENG Antibody (Center) (Cat# 102-11006). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ENG gene.
ENG Antibody (Center) (Cat# 102-11006) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
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