This ENT1(Slc29a1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-260 amino acids from human ENT1(Slc29a1).
Host Species
Rabbit
Clonality
Polyclonal
Species
Human
Introduction
ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.
Specificity
Other Names
SLC29A1; ENT1; Equilibrative nucleoside transporter 1; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Nucleoside transporter, es-type; Solute carrier family 29 member 1
Western blot analysis of anti-ENT1(Slc29a1) Antibody (S254) (Cat# 102-10835) in 293 cell line lysates (35ug/lane). ENT1 (arrow) was detected using the purified Pab.
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
