Rabbit Anti-Human F2RL2 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O00254 |
| Gene Id | 2151 |
| Gene Symbols | F2RL2 |
| Protein Name / Synonyms | F2RL2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This F2RL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human F2RL2. |
| Concentration (lot specific) | 0.390 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.
Specificity
Other Names
F2RL2; PAR3; Proteinase-activated receptor 3; Coagulation factor II receptor-like 2; Thrombin receptor-like 2
NCBI Accession #
NP_001243495.1;NP_004092.1
Other Accession #
NP_004092.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
42508
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | F2RL2 Antibody (N-term) (Cat# 102-11483) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the F2RL2 antibody detected the F2RL2 protein (arrow). |
 | F2RL2 Antibody (N-term) (Cat# 102-11483)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of F2RL2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.