Rabbit Anti-Human FCGR3A (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P08637 |
| Gene Id | 2214 |
| Gene Symbols | FCGR3A |
| Protein Name / Synonyms | FCGR3A (C-term) |
| Clonality | Polyclonal |
| Preparation | This FCGR3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 amino acids from the C-terminal region of human FCGR3A. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specificity
Other Names
FCGR3A; CD16A; FCG3; FCGR3; IGFR3; Low affinity immunoglobulin gamma Fc region receptor III-A; CD16a antigen; Fc-gamma RIII-alpha; FcR-10; IgG Fc receptor III-2; CD_antigen=CD16a; Flags: Precursor
NCBI Accession #
NP_000560.5;NP_001121064.1;NP_001121065.1;NP_001121067.1;NP_001121068.1
Other Accession #
NP_001121067.1; NP_001121064.1; NP_000560.5; NP_001121068.1; NP_001121065.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
29089
Recommended Dilutions
WB: 1:1000
 | FCGR3A Antibody (C-term) (Cat# 102-12042) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the FCGR3A antibody detected the FCGR3A protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.