Rabbit Anti-Human FOXO3 (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O43524 |
| Gene Id | 2309 |
| Gene Symbols | FOXO3 |
| Protein Name / Synonyms | FOXO3 (Center) |
| Clonality | Polyclonal |
| Preparation | This FOXO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-253 amino acids from the Central region of human FOXO3. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF |
| Research Area | Cancer, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
Specificity
Predicted Reactivity
Mouse
Other Names
FOXO3; FKHRL1; FOXO3A; Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1
NCBI Accession #
NP_001446.1;NP_963853.1
Other Accession #
Q9WVH4; NP_963853.1; NP_001446.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
71277
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; IF: 1:10-50
 | FOXO3 Antibody (Center) (Cat# 102-12345) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FOXO3 antibody detected the FOXO3 protein (arrow). |
 | FOXO3 Antibody (Center) (Cat# 102-12345)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ANKS1B FOXO3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of FOXO3 Antibody (Center)(Cat# 102-12345) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.