Rabbit Anti-Human GAD2 (Center)

Rabbit Anti-Human GAD2 (Center) Antibody, 400 ul
In stock

Product Description


Size 400 µl
Protein Name / Synonyms GAD2 (Center)
Accession Number Q05329
Gene Symbols GAD2
Gene Id 2572
Concentration (lot specific) 0.470 mg/ml
Preparation This GAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human GAD2.
Host Species Rabbit
Clonality Polyclonal
Species Human


This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.


Predicted Reactivity
Mouse, Rat, Pig
Other Names
GAD2; GAD65; Glutamate decarboxylase 2; 65 kDa glutamic acid decarboxylase; Glutamate decarboxylase 65 kDa isoform
NCBI Accession #
Other Accession #
Q05683; P48321; P48320; NP_001127838.1; NP_000809.1


Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; IF: 1:10-50
GAD2 Antibody (Center) (Cat# 102-10949) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the GAD2 antibody detected the GAD2 protein (arrow).
GAD2 Antibody (Center) (Cat# 102-10949)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GAD2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Confocal immunofluorescent analysis of GAD2 Antibody (Center)(Cat# 102-10949) with 293 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Antigen Source



2-8°C (short-term); -20°C (long-term)
12 months from the date of shipment when stored properly.
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