Rabbit Anti-Human GALNS (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P34059 |
| Gene Id | 2588 |
| Gene Symbols | GALNS |
| Protein Name / Synonyms | GALNS (Center) |
| Clonality | Polyclonal |
| Preparation | This GALNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-263 amino acids from the Central region of human GALNS. |
| Concentration (lot specific) | 0.480 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq].
Specificity
Predicted Reactivity
Mouse, Rat, Pig
Other Names
GALNS; N-acetylgalactosamine-6-sulfatase; Chondroitinsulfatase; Galactose-6-sulfate sulfatase; N-acetylgalactosamine-6-sulfate sulfatase
NCBI Accession #
NP_000503.1
Other Accession #
Q32KJ6; Q8WNQ7; Q571E4; NP_000503.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
58026
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; IF: 1:10-50; FC: 1:10-50
 | GALNS Antibody (Center) (Cat# 102-11181) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the GALNS antibody detected the GALNS protein (arrow). |
 | GALNS Antibody (Center) (Cat# 102-11181)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GALNS Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of GALNS Antibody (Center)(Cat# 102-11181) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). |
 | GALNS Antibody (Center) (Cat# 102-11181) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.