Rabbit Anti-Human GALNT4 (N-term)

Rabbit Anti-Human GALNT4 (N-term) Antibody, 400 ul
$334.00
In stock
Code:
102-10588
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Product Description

Specifications

Size 400 µl
Protein Name / Synonyms GALNT4 (N-term)
Accession Number Q8N4A0
Gene Symbols GALNT4
Gene Id 8693
Concentration (lot specific) 0.5 mg/ml
Preparation This GALNT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human GALNT4.
Host Species Rabbit
Clonality Polyclonal
Species Human

Introduction

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon.

Specificity

Predicted Reactivity
Mouse
Other Names
GALNT4; Polypeptide N-acetylgalactosaminyltransferase 4; Polypeptide GalNAc transferase 4; Protein-UDP acetylgalactosaminyltransferase 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4
NCBI Accession #
NP_001186711.1;NP_003765.2
Other Accession #
O08832; NP_003765.2

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
66666
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
GALNT4 Antibody (N-term) (Cat# 102-10588) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the GALNT4 antibody detected the GALNT4 protein (arrow).
GALNT4 Antibody (N-term) (Cat# 102-10588) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
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