Rabbit Anti-Human HDAC1 (C-term)

Rabbit Anti-Human HDAC1 (C-term) Antibody, 400 ul
In stock

Product Description


Size 400 µl
Protein Name / Synonyms HDAC1 (C-term)
Accession Number Q13547
Gene Symbols HDAC1
Gene Id 3065
Concentration (lot specific) 2.0 mg/ml
Preparation This HDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 449-482 amino acids from the C-terminal region of human HDAC1.
Host Species Rabbit
Clonality Polyclonal
Species Human


Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.


Predicted Reactivity
Other Names
HDAC1; RPD3L1; Histone deacetylase 1
NCBI Accession #
Other Accession #


Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
Recommended Dilutions
IF: 1:10-50; WB: 1:1000
Fluorescent image of Hela cell stained with HDAC1 Antibody (C-term)(Cat# 102-10902/SH040527D).Hela cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with HDAC1 primary antibody (1:25, 1 h at 37°). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°).HDAC1 immunoreactivity is localized to Nucleus significantly.
The anti-HDAC1 Pab (Cat# 102-10902) is used in Western blot to detect HDAC1 in ZR-75-1 cell lysate.
The anti-HDAC1 Pab (Cat# 102-10902) was used in Western Blot to detect HDAC1 in HEK293 cells. Knockdown of HDAC1 using siRNA against HDAC1 showed a significant decrease of HDAC1 protein using this anti-HDAC1 Pab in HEK293 cells.

Antigen Source



2-8°C (short-term); -20°C (long-term)
12 months from the date of shipment when stored properly.
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