Introduction
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq].
Specificity
Predicted Reactivity
Mouse, Rat, Zebrafish, Bovine, Chicken, Drosophila, C.Elegans, Pig, Rabbit, Xenopus
Other Names
HIST2H3A; Histone H3.2; Histone H3/m; Histone H3/o
NCBI Accession #
NP_001005464.1;NP_001116847.1;NP_066403.2
Other Accession #
P02299; P08898; P02302; P02301; Q6NXT2; Q6PI79; P84245; P84246; Q71LE2; P84244; P84243; P84249; Q6PI20; P84247; Q5E9F8; Q10453; P84233; P84228; Q4QRF4; P84229; P84227; Q6LED0; P68433; P68431; P68432; Q16695; NP_066403.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
15388
Recommended Dilutions
WB: 1:1000
 | HIST2H3A Antibody (C-term) (Cat# 102-14370) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the HIST2H3A antibody detected the HIST2H3A protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.