Rabbit Anti-Human HSP90B1 (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P14625 |
| Gene Id | 7184 |
| Gene Symbols | HSP90B1 |
| Protein Name / Synonyms | HSP90B1 (Center) |
| Clonality | Polyclonal |
| Preparation | This HSP90B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 460-487 amino acids from the Central region of human HSP90B1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | IHC-P, Western Blotting, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is an endoplasmic reticulum HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1; MIM 140571) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).
Specificity
Predicted Reactivity
Monkey
Other Names
HSP90B1; GRP94; TRA1; Endoplasmin; 94 kDa glucose-regulated protein; Heat shock protein 90 kDa beta member 1; Tumor rejection antigen 1; gp96 homolog
NCBI Accession #
NP_003290.1
Other Accession #
Q4R520; NP_003290.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
92469
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | HSP90B1 Antibody (Center) (Cat# 102-11315) western blot analysis in Hela,MCF-7,mouse C2C12 cell line lysates (35ug/lane).This demonstrates the HSP90B1 antibody detected the HSP90B1 protein (arrow). |
 | HSP90B1 Antibody (Center) (Cat# 102-11315)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HSP90B1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | HSP90B1 Antibody (Center) (Cat# 102-11315) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.