Rabbit Anti-Human KHSRP (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q92945 |
| Gene Id | 8570 |
| Gene Symbols | KHSRP |
| Protein Name / Synonyms | KHSRP (N-term) |
| Clonality | Polyclonal |
| Preparation | This KHSRP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the N-terminal region of human KHSRP. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). It is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE) and activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Specificity
Predicted Reactivity
Chicken
Other Names
KHSRP; FUBP2; Far upstream element-binding protein 2; KH type-splicing regulatory protein; p75
NCBI Accession #
NP_003676.2
Other Accession #
Q8UVD9
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
73115
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; IF: 1:10-50
 | Western blot analysis of KHSRP Antibody (N-term) (Cat# 102-16981) in T47D cell line lysates (35ug/lane). KHSRP (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human brain with KHSRP Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Immunofluorescence analysis of KHSRP Antibody (N-term) with paraffin-embedded human brain tissue . 0.05 mg/ml primary antibody was followed by FITC-conjugated goat anti-rabbit lgG (whole molecule). FITC emits green fluorescence. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.