Rabbit Anti-Human KREMEN2 (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q8NCW0 |
| Gene Id | 79412 |
| Gene Symbols | KREMEN2 |
| Protein Name / Synonyms | KREMEN2 (Center) |
| Clonality | Polyclonal |
| Preparation | This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Specificity
Other Names
KREMEN2; KRM2; Kremen protein 2; Dickkopf receptor 2; Kringle domain-containing transmembrane protein 2; Kringle-containing protein marking the eye and the nose
NCBI Accession #
NP_001240654.1;NP_001240655.1;NP_078783.1;NP_757384.1
Other Accession #
NP_757384.1; NP_078783.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
48849
Recommended Dilutions
WB: 1:1000
 | KREMEN2 Antibody (Center) (Cat# 102-11846) western blot analysis in ZR-75-1,K562,NCI-H460 cell line lysates (35ug/lane).This demonstrates the KREMEN2 antibody detected the KREMEN2 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.