This KRT80 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human KRT80.
Host Species
Rabbit
Clonality
Polyclonal
Species
Human
Introduction
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.
Specificity
Other Names
KRT80; KB20; Keratin, type II cytoskeletal 80; Cytokeratin-80; Keratin-80; Type-II keratin Kb20
KRT80 Antibody (C-term) (Cat# 102-10836) western blot analysis in NCI-H460,SK-BR-3 cell line lysates (35ug/lane).This demonstrates the KRT80 antibody detected the KRT80 protein (arrow).
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
