Rabbit Anti-Human LIN7C (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9NUP9 |
| Gene Id | 55327 |
| Gene Symbols | LIN7C |
| Protein Name / Synonyms | LIN7C (C-term) |
| Clonality | Polyclonal |
| Preparation | This LIN7C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human LIN7C. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | IHC-P, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine
Other Names
LIN7C; MALS3; VELI3; Protein lin-7 homolog C; Mammalian lin-seven protein 3; Vertebrate lin-7 homolog 3
NCBI Accession #
NP_060832.1
Other Accession #
Q792I0; O88952; Q0P5F3; NP_060832.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
21834
Recommended Dilutions
IHC: 1:10-50; WB: 1:1000
 | LIN7C Antibdy (C-term) (Cat# 102-11739)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of LIN7C Antibdy (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | LIN7C Antibody (C-term) (Cat# 102-11739) western blot analysis in MCF-7,NCI-H292 cell line lysates (35ug/lane).This demonstrates the LIN7C antibody detected the LIN7C protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.